Cenforce 100 typically starts working within 30 to 60 minutes after oral intake. However, its effectiveness can vary based on individual metabolism, diet, and overall health. For the fastest results, take it on an empty stomach with a glass of water. High-fat meals can delay their absorption and reduce their impact. Once active, its effects can last up to 4–6 hours, allowing flexibility for sexual activity. It’s important to note that sexual stimulation is required for Cenforce 100 to work. Avoid alcohol and grapefruit juice, as they may interfere with the drug’s performance. Always follow your doctor's dosage guidance.